Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5513692 | 0.81 | TDP1 (0.58) | TDP1MAPTGAAKDM4EGLA | |
| SCHEMBL11675308 | 0.79 | TDP1 (0.56) | TDP1MAPTGAAKDM4EGLA | |
| SCHEMBL13303658 | 0.78 | ALDH1A1 (0.52) | TDP1MAPTGAAKDM4ETHRB | |
| SCHEMBL16280936 | 0.78 | MAPT (0.86) | TDP1MAPTGAAKDM4EGLA | |
| SCHEMBL18520106 | 0.78 | TDP1 (0.54) | TDP1MAPTGAAKDM4EGLA | |
| SCHEMBL14043751 | 0.76 | PPARG (0.43) | MAPTGAATHRBRAB9AKMT2A | |
| SCHEMBL14043750 | 0.76 | KMT2A (0.53) | MAPTKDM4EPARP10KMT2AALDH1A1 | |
| SCHEMBL13178490 | 0.76 | ALDH1A1 (0.41) | TDP1MAPTGAAKDM4EGLA | |
| SCHEMBL629277 | 0.76 | TDP1 (0.53) | TDP1MAPTGAAKDM4EGLA | |
| SCHEMBL4100461 | 0.75 | TDP1 (0.50) | TDP1MAPTGAAKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063402-A1 | SUBSTITUTED BENZYL AND PHENYLSULFONYL TRIAZOLONES, AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-10 | — | — | WO | disclosed |