SCHEMBL7917404

SCHEMBL7917404

CCCCCCCC1CCC(c2ccc(OC(F)(F)C(F)C(F)(F)F)cc2)CC1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
SPHK1 Q9NYA1 11/20 0.38
MAPT P10636 2/20 0.38
GAA P10253 1/20 0.38
CYP2C9 P11712 1/20 0.37
LMNA P02545 1/20 0.36
MEN1 O00255 1/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 1/20 0.36
SPHK2 Q9NRA0 7/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913769 1.00 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10SPHK1MAPT
SCHEMBL7914150 0.99 ALDH1A1 (0.40) ALDH1A1TSHRHSD17B10SPHK1MAPT
SCHEMBL7911994 0.97 ALDH1A1 (0.37) ALDH1A1TSHRHSD17B10SPHK1MAPT
SCHEMBL7903446 0.97 ALDH1A1 (0.37) ALDH1A1TSHRHSD17B10SPHK1MAPT
SCHEMBL7911809 0.97 ALDH1A1 (0.37) ALDH1A1TSHRHSD17B10SPHK1MAPT
SCHEMBL7911974 0.97 ALDH1A1 (0.37) ALDH1A1TSHRHSD17B10SPHK1MAPT
SCHEMBL7912204 0.97 MAPT (0.38) ALDH1A1TSHRHSD17B10SPHK1MAPT
SCHEMBL7917348 0.95 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10SPHK1MAPT
SCHEMBL7911232 0.95 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10SPHK1MAPT
SCHEMBL7903622 0.95 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10SPHK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed