SCHEMBL7917510

SCHEMBL7917510

CC(c1ccc(Cl)cc1)c1c(Cl)cc(N2N=CCNC2=O)cc1Cl

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NR1I2 O75469 1/20 0.34
TSHR P16473 1/20 0.31
NPBWR1 P48145 1/20 0.31
MCHR1 Q99705 1/20 0.31
FFAR2 O15552 1/20 0.31
FPR2 P25090 1/20 0.31
PROKR1 Q8TCW9 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
HSD11B1 P28845 2/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7917049 0.85 MEN1 (0.34) MEN1KMT2ANR1I2FPR2PROKR1
SCHEMBL7919693 0.85 MEN1 (0.34) MEN1KMT2ANR1I2FPR2PROKR1
SCHEMBL7917757 0.83 FPR2 (0.33) MEN1KMT2ANR1I2FPR2PROKR1
SCHEMBL7917733 0.83 MEN1 (0.33) MEN1KMT2ANR1I2TSHRLMNA
SCHEMBL7919224 0.83 MEN1 (0.33) MEN1KMT2ANR1I2TSHRALDH1A1
SCHEMBL7917711 0.82 MEN1 (0.31) MEN1KMT2ANR1I2TSHRALDH1A1
SCHEMBL7922600 0.82 MEN1 (0.32) MEN1KMT2ANR1I2TSHR
SCHEMBL7917015 0.82 DRD4 (0.32) MEN1KMT2ANR1I2TSHRFPR2
SCHEMBL7838454 0.82 MEN1 (0.54) MEN1KMT2ANR1I2FPR2PROKR1
SCHEMBL7917009 0.82 FPR2 (0.35) MEN1KMT2ANR1I2TSHRNPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648760-B1 Triazine derivative, production and use thereof TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-01-27 EP claimed
US-6211178-B1 ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-04-03 US disclosed
US-5994355-A ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-11-30 US disclosed
EP-0648760-B1 Triazine derivative, production and use thereof TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-01-27 EP disclosed
EP-0648760-A2 Triazine derivative, production and use thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-04-19 EP disclosed