Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2019716 | 0.76 | MEN1 (0.50) | MAOAMEN1KMT2ATDP1MAPT | |
| SCHEMBL19585998 | 0.76 | MEN1 (0.50) | MAOAMEN1KMT2ATDP1IDO1 | |
| SCHEMBL17065387 | 0.73 | MEN1 (0.47) | MAOAMEN1KMT2ATDP1IDO1 | |
| SCHEMBL5799878 | 0.72 | MEN1 (0.78) | MAOAMEN1KMT2ATDP1IDO1 | |
| SCHEMBL1654 | 0.72 | MEN1 (0.78) | MAOAMEN1KMT2ATDP1IDO1 | |
| Benzene SCHEMBL11697595 | 0.72 | MEN1 (0.78) | MAOAMEN1KMT2ATDP1IDO1 | |
| SCHEMBL15777303 | 0.72 | KDM1A (0.63) | MAOAMAOBKDM1A | |
| SCHEMBL15787699 | 0.72 | KDM1A (0.63) | MAOAMAOBKDM1A | |
| SCHEMBL23023065 | 0.72 | MEN1 (0.45) | MAOAMEN1KMT2ATDP1MAPT | |
| SCHEMBL7277140 | 0.72 | MEN1 (0.45) | MAOAMEN1KMT2ATDP1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010082612-A1 | IMIDAZOTHIAZOLE DERIVATIVE HAVING PROLINE RING STRUCTURE | 第一三共株式会社 (JP) | 2010-07-22 | — | — | WO | disclosed |