SCHEMBL1654

SCHEMBL1654

c1ccc(CNCc2ccccc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.78
KMT2A Q03164 1/20 0.78
TDP1 Q9NUW8 1/20 0.78
MAOA P21397 1/20 0.67
MAPT P10636 3/20 0.64
CHRM2 P08172 1/20 0.64
GAA P10253 1/20 0.64
IDO1 P14902 2/20 0.60
THRB P10828 1/20 0.60
PKM P14618 1/20 0.60
BCHE P06276 1/20 0.60
ADH1B P00325 1/20 0.59
ADH1C P00326 1/20 0.59
ADH1A P07327 1/20 0.59
ADH7 P40394 1/20 0.59
SIGMAR1 Q99720 3/20 0.58
CYP3A4 P08684 2/20 0.57
KDM4E B2RXH2 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5799878 1.00 MEN1 (0.78) MEN1KMT2ATDP1MAOAMAPT
Benzene SCHEMBL11697595 1.00 MEN1 (0.78) MEN1KMT2ATDP1MAOAMAPT
SCHEMBL3990993 0.97 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT
Ammonia Solution, Strong SCHEMBL2064651 0.97 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT
Fluoride SCHEMBL634375 0.97 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT
Water SCHEMBL11666905 0.97 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT
Hydrochloric Acid SCHEMBL1862144 0.97 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT
Bromide SCHEMBL998627 0.97 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT
SCHEMBL21550054 0.97 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT
SCHEMBL30223761 0.97 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 49627 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037194-A Preparation method of functional poly-lipoic acid material based on lipoic acid-amine molecular eutectic system 西安交通大学 2026-05-15 CN claimed
CN-122010747-A Photochemical synthesis method of fluorine-containing tertiary amine 贵州医科大学 2026-05-12 CN claimed
CN-122011028-A Method for efficiently preparing various substituted chiral phosphoramides 上海交通大学 2026-05-12 CN claimed
CN-122010806-A Method for synthesizing high-yield anti-sulfuration reducing agent HTS with low sodium salt content 山东尚舜化工有限公司 2026-05-12 CN claimed
US-12624060-B2 Ruthenium complexes, methods of their preparation and application thereof in olefin cross metathesis APEIRON SYNTHESIS S.A. (PL) 2026-05-12 US claimed
US-20260070799-A1 ORGANIC HEXACYANOFERRATES: SYNTHESES AND USES WALKER CANCER RESEARCH INSTITUTE, INC. (US) 2026-03-12 US claimed
US-12552931-B2 Dihydroxy lactam based polymers, compositions and applications thereof ISP INVESTMENTS LLC (US) 2026-02-17 US claimed
EP-4673125-A1 R-MDMA FOR TREATMENT OF PAIN Mind Medicine, Inc. (US) 2026-01-07 EP claimed
US-20250387385-A1 TREATMENT FOR GLOMERULAR DISEASES ZYDUS LIFESCIENCES LIMITED (IN) 2025-12-25 US claimed
US-20250376432-A1 PROCESS FOR PREPARING MODULATORS OF EUKARYOTIC INITIATION FACTOR 2B DENALI THERAPEUTICS INC (US) 2025-12-11 US claimed
US-3967835-A Pressure-sensitive copying material HODOGAYA CHEMICAL CO., LTD. (JA) 1976-07-06 US claimed
US-3960857-A Urea additives for sulfur vulcanizable polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-06-01 US claimed
US-3954729-A FROM A SECONDARY AMINE, CARBONYL SULFIDE, AND AN ALKYL HALIDE IHARA CHEMICAL INDUSTRY CO., LTD. (JA) 1976-05-04 US claimed
US-3945941-A POLYETHYLENE OR POLYPROPYLENE STORAGETANK LINERS OXIRANE CORPORATION (US) 1976-03-23 US claimed
US-3944544-A BACTERICIDE E. R. SQUIBB & SONS, INC. (US) 1976-03-16 US claimed
US-3937691-A Manufacture of poly (α-olefins) BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-02-10 US claimed
US-3932396-A ANTIBIOTICS E. R. SQUIBB & SONS, INC. (US) 1976-01-13 US claimed
US-3932397-A BACTERICIDES E. R. SQUIBB & SONS, INC. (US) 1976-01-13 US claimed
US-3931153-A BACTERICIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-01-06 US claimed
US-3930672-A Pressure-sensitive copying paper containing lactone compounds derived from pyridine-carboxylic acid HODOGAYA CHEMICAL CO., LTD. (JA) 1976-01-06 US claimed