Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.92 |
| ▸ | ITGAV | P06756 | 20/20 | 0.92 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325096 | 0.96 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL6944353 | 0.93 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7077079 | 0.91 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL6946521 | 0.91 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL31321063 | 0.91 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL245523 | 0.91 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL5165662 | 0.90 | ITGB3 (0.86) | ITGB3ITGAVITGA2B | |
| SCHEMBL5972719 | 0.89 | ITGB3 (0.85) | ITGB3ITGAVITGA2B | |
| SCHEMBL6130318 | 0.88 | ITGB3 (0.84) | ITGB3ITGAVITGA2B | |
| SCHEMBL7501339 | 0.88 | ITGB3 (0.81) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140183-A1 | USE OF A MATRIX METALLOPROTEINASE INHIBITOR AND AN INTEGRIN ANTAGONIST IN THE TREATMENT OF NEOPLASIA | G.D. SEARLE & CO. (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000038719-A1 | USE OF A MATRIX METALLOPROTEINASE INHIBITOR AND AN INTEGRIN ANTAGONIST IN THE TREATMENT OF NEOPLASIA | G.D. SEARLE & CO. (US) | 2000-07-06 | — | — | WO | claimed |
| EP-1140183-A1 | USE OF A MATRIX METALLOPROTEINASE INHIBITOR AND AN INTEGRIN ANTAGONIST IN THE TREATMENT OF NEOPLASIA | G.D. SEARLE & CO. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000038719-A1 | USE OF A MATRIX METALLOPROTEINASE INHIBITOR AND AN INTEGRIN ANTAGONIST IN THE TREATMENT OF NEOPLASIA | G.D. SEARLE & CO. (US) | 2000-07-06 | — | — | WO | disclosed |