Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 9/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811421 | 0.91 | KMT2A (0.49) | KMT2ACACNA1BAPBA1RAB9ANPC1 | |
| SCHEMBL6814537 | 0.83 | KMT2A (0.42) | KMT2ACACNA1BAPBA1RAB9ANPC1 | |
| SCHEMBL6814920 | 0.83 | MTOR (0.47) | KMT2ARAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL6815183 | 0.79 | KMT2A (0.52) | KMT2ACACNA1BAPBA1RAB9ANPC1 | |
| SCHEMBL6814835 | 0.77 | KMT2A (0.50) | KMT2ACACNA1BAPBA1RAB9ANPC1 | |
| SCHEMBL6814954 | 0.77 | KMT2A (0.51) | KMT2ACACNA1BAPBA1RAB9ANPC1 | |
| SCHEMBL6811423 | 0.75 | KMT2A (0.47) | KMT2ACACNA1BAPBA1RAB9ANPC1 | |
| SCHEMBL6814796 | 0.74 | LMNA (0.45) | KMT2ARAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL6815540 | 0.74 | LMNA (0.45) | KMT2ARAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL6811224 | 0.73 | LMNA (0.45) | KMT2ARAB9ANPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207715-B1 | USEFUL IN THERAPY OF DISEASES ASSOCIATED WITH HERPES VIRUSES INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES-6 AND -7, AND KAPOSI HERPES VIRUS | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-27 | — | — | US | disclosed |