Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918526 | 1.00 | KMT2A (0.44) | KMT2AMEN1NPSR1MAPK1TSHR | |
| SCHEMBL7924191 | 0.84 | KMT2A (0.42) | KMT2AMEN1NPSR1MAPK1TSHR | |
| SCHEMBL7924196 | 0.84 | KMT2A (0.42) | KMT2AMEN1NPSR1MAPK1TSHR | |
| SCHEMBL8321000 | 0.77 | MAOB (0.43) | LMNA | |
| SCHEMBL8319363 | 0.77 | NQO1 (0.44) | TSHRSMN1; SMN2LMNA | |
| SCHEMBL8319360 | 0.77 | NQO1 (0.44) | TSHRSMN1; SMN2LMNA | |
| SCHEMBL8320991 | 0.77 | MAOB (0.43) | LMNA | |
| SCHEMBL8319358 | 0.77 | GRIN2D (0.40) | KMT2AMEN1MAPK1TSHRPOLB | |
| SCHEMBL8319359 | 0.77 | GRIN2D (0.40) | KMT2AMEN1MAPK1TSHRPOLB | |
| SCHEMBL11044678 | 0.75 | MEN1 (0.52) | KMT2AMEN1NPSR1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811596-B1 | Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds | BASF AG (DE) | 2001-07-25 | — | — | EP | disclosed |
| US-6262319-B1 | BROMINATION OF THE CORRESPONDING ALCOHOL COMPOUND | AMERICAN CYANAMID CO. | 2001-07-17 | — | — | US | disclosed |
| US-5892131-A | Process for the preparation of pesticidal fluoroolefin compounds | AMERICAN CYANAMID COMPANY (US) | 1999-04-06 | — | — | US | disclosed |
| US-5880162-A | INSECTICIDES FOR SOIL BORNE INSECT PESTS | BRITISH TECHNOLOGY GROUP, LTD. (GB) | 1999-03-09 | — | — | US | disclosed |
| EP-0811596-A1 | Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |
| CN-1147242-A | Pesticidal fluoroolefins | BRITISH TECH GROUP LTD (GB) | 1997-04-09 | — | — | CN | disclosed |
| EP-0757668-A1 | PESTICIDAL FLUOROOLEFINS | British Technology Group Ltd. (GB) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029887-A1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |