Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924196 | 1.00 | KMT2A (0.42) | KMT2AMEN1NPSR1GSK3BMAPK1 | |
| SCHEMBL7918527 | 0.84 | KMT2A (0.44) | KMT2AMEN1NPSR1MAPK1TSHR | |
| SCHEMBL7918526 | 0.84 | KMT2A (0.44) | KMT2AMEN1NPSR1MAPK1TSHR | |
| SCHEMBL7620431 | 0.76 | MEN1 (0.50) | KMT2AMEN1NPSR1MAPK1TSHR | |
| SCHEMBL8319358 | 0.75 | GRIN2D (0.40) | KMT2AMEN1MAPK1TSHRPOLB | |
| SCHEMBL8319359 | 0.75 | GRIN2D (0.40) | KMT2AMEN1MAPK1TSHRPOLB | |
| SCHEMBL11044678 | 0.74 | MEN1 (0.52) | KMT2AMEN1NPSR1MAPK1TSHR | |
| SCHEMBL8585849 | 0.70 | SMN1; SMN2 (0.39) | KMT2AMEN1NPSR1POLBBCL2 | |
| SCHEMBL8585853 | 0.70 | SMN1; SMN2 (0.39) | KMT2AMEN1NPSR1POLBBCL2 | |
| SCHEMBL7624113 | 0.69 | MEN1 (0.42) | KMT2AMEN1NPSR1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811596-B1 | Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds | BASF AG (DE) | 2001-07-25 | — | — | EP | claimed |
| US-6262319-B1 | BROMINATION OF THE CORRESPONDING ALCOHOL COMPOUND | AMERICAN CYANAMID CO. | 2001-07-17 | — | — | US | claimed |
| EP-0811596-A1 | Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | claimed |
| EP-0811596-B1 | Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds | BASF AG (DE) | 2001-07-25 | — | — | EP | disclosed |
| US-6262319-B1 | BROMINATION OF THE CORRESPONDING ALCOHOL COMPOUND | AMERICAN CYANAMID CO. | 2001-07-17 | — | — | US | disclosed |
| US-5892131-A | Process for the preparation of pesticidal fluoroolefin compounds | AMERICAN CYANAMID COMPANY (US) | 1999-04-06 | — | — | US | disclosed |
| EP-0811596-A1 | Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |