SCHEMBL7918675

SCHEMBL7918675

Clc1cccc2c(-c3ccccc3)c3c(Cl)cccc3cc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.48
CYP2A6 P11509 4/20 0.48
ESR1 P03372 6/20 0.42
ESR2 Q92731 5/20 0.42
MAP2 P11137 1/20 0.37
DYRK1A Q13627 1/20 0.36
THRA P10827 1/20 0.35
THRB P10828 1/20 0.35
AHR P35869 2/20 0.34
ERBB2 P04626 1/20 0.34
FYN P06241 1/20 0.34
MAOA P21397 1/20 0.34
ACHE P22303 1/20 0.34
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NQO2 P16083 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27287007 0.88 CYP1A2 (0.45) CYP1A2CYP2A6ESR1ESR2MAP2
SCHEMBL28326311 0.86 CYP1A2 (0.52) CYP1A2CYP2A6ESR1ESR2MAP2
SCHEMBL22512513 0.81 CYP2A6 (0.50) CYP1A2CYP2A6ESR1ESR2MAP2
SCHEMBL1758344 0.80 CYP1A2 (0.42) CYP1A2CYP2A6ESR1ESR2MAP2
SCHEMBL29367682 0.80 CYP1A2 (0.42) CYP1A2CYP2A6ESR1ESR2MAP2
SCHEMBL28391800 0.79 CYP1A2 (0.46) CYP1A2CYP2A6ESR1ESR2MAP2
SCHEMBL10405354 0.76 CYP1A2 (0.52) CYP1A2CYP2A6ESR1ESR2THRB
SCHEMBL4316535 0.75 ESR1 (0.55) CYP1A2ESR1ESR2ACHEKDM4E
SCHEMBL28811029 0.74 ESR1 (0.50) CYP1A2CYP2A6ESR1ESR2DYRK1A
SCHEMBL5470663 0.74 ESR1 (0.58) CYP1A2ESR1ESR2ACHEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed