Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918102 | 0.88 | HTT (0.34) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7918099 | 0.88 | TAAR1 (0.31) | TAAR1ADRA2A | |
| SCHEMBL7919909 | 0.85 | TAAR1 (0.34) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7913281 | 0.80 | TAAR1 (0.40) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7920016 | 0.80 | TAAR1 (0.40) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7916197 | 0.80 | TAAR1 (0.40) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7913169 | 0.80 | TAAR1 (0.33) | TAAR1ADRA2ABACE1MEN1KMT2A | |
| SCHEMBL7923354 | 0.79 | TAAR1 (0.39) | TAAR1ADRA2ABACE1MEN1ALDH1A1 | |
| SCHEMBL7923311 | 0.79 | TAAR1 (0.34) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7911125 | 0.78 | TSHR (0.33) | TAAR1ADRA2ABACE1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042475-A1 | SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |