Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.33 |
| ▸ | CTSD | P07339 | 2/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913192 | 0.87 | ROCK2 (0.34) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7918694 | 0.85 | TAAR1 (0.35) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7913188 | 0.72 | BACE1 (0.39) | BACE1 | |
| SCHEMBL7911146 | 0.72 | BACE1 (0.47) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7916197 | 0.70 | TAAR1 (0.40) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7920016 | 0.70 | TAAR1 (0.40) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7923311 | 0.69 | TAAR1 (0.34) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7920108 | 0.68 | BACE1 (0.45) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7920233 | 0.65 | BRD4 (0.45) | — | |
| SCHEMBL7917963 | 0.65 | BACE1 (0.43) | TAAR1ADRA2ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042475-A1 | SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |