SCHEMBL7918865

SCHEMBL7918865

[Na].c1ccc(Cc2cccc3ccccc23)cc1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.52
CYP1A2 P05177 2/20 0.52
CYP2C9 P11712 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.48
GPR55 Q9Y2T6 1/20 0.47
ADRA2A P08913 1/20 0.47
ADRA2B P18089 1/20 0.47
ADRA2C P18825 1/20 0.47
ADRA1D P25100 1/20 0.47
ADRA1A P35348 1/20 0.47
ADRA1B P35368 1/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31738884 0.98 CYP2C19 (0.54) CYP2C19CYP1A2CYP2C9TDP1CYP3A4
SCHEMBL147085 0.98 CYP2C19 (0.54) CYP2C19CYP1A2CYP2C9TDP1CYP3A4
Hydrogen Sulfide SCHEMBL28838423 0.96 CYP2C19 (0.52) CYP2C19CYP1A2CYP2C9TDP1CYP3A4
SCHEMBL7918863 0.96 CYP2C19 (0.52) CYP2C19CYP1A2CYP2C9TDP1CYP3A4
Methane SCHEMBL27919160 0.94 CYP2C19 (0.50) CYP2C19CYP1A2CYP2C9TDP1CYP3A4
Formaldehyde SCHEMBL27716206 0.92 TDP1 (0.53) CYP2C19CYP1A2CYP2C9TDP1CYP3A4
Dimethylamine SCHEMBL11571354 0.92 CYP2C19 (0.50) CYP2C19CYP1A2CYP2C9TDP1CYP3A4
SCHEMBL7624046 0.90 SIGMAR1 (0.48) CYP2C19CYP1A2CYP2C9TDP1CYP3A4
SCHEMBL659517 0.86 CYP2C19 (0.60) CYP2C19CYP1A2CYP2C9TDP1CYP3A4
SCHEMBL4667060 0.86 CYP2C19 (0.60) CYP2C19CYP1A2CYP2C9TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235067-B1 LIQUID HYDROCARBON FUEL AND WATER SUPERCRITICAL MIXTURE EMITTER NOZZLES MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2001-05-22 US disclosed