Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 16/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920700 | 0.92 | ALDH1A1 (0.52) | ALDH1A1CYP2C9TSHRSMN1; SMN2HTT | |
| SCHEMBL7911871 | 0.92 | ALDH1A1 (0.57) | ALDH1A1CYP2C9CYP2C19TSHRSMN1; SMN2 | |
| SCHEMBL7923992 | 0.90 | TSHR (0.51) | ALDH1A1CYP2C9CYP2C19TSHRSMN1; SMN2 | |
| SCHEMBL7924113 | 0.89 | ALDH1A1 (0.64) | ALDH1A1CYP2C9CYP2C19TSHRSMN1; SMN2 | |
| SCHEMBL7911889 | 0.87 | TSHR (0.48) | ALDH1A1CYP2C9CYP2C19TSHRSMN1; SMN2 | |
| SCHEMBL7919288 | 0.86 | ALDH1A1 (0.66) | ALDH1A1CYP2C9CYP2C19TSHRSMN1; SMN2 | |
| SCHEMBL7918962 | 0.84 | ALDH1A1 (0.48) | ALDH1A1CYP2C9CYP2C19TSHRSMN1; SMN2 | |
| SCHEMBL7920704 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CYP2C9TSHRSMN1; SMN2HTT | |
| SCHEMBL7924116 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CYP2C9TSHRSMN1; SMN2HTT | |
| SCHEMBL7911820 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP2C19TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811375-B1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA LTD (JP) | 2001-01-03 | — | — | EP | disclosed |
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |
| EP-0811375-A1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA, LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |