Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27372929 | 0.78 | CYP11B1 (0.33) | KDM4EHTR2ADRD2TP53LMNA | |
| SCHEMBL5859366 | 0.78 | CYP11B1 (0.33) | KDM4EHTR2ADRD2TP53LMNA | |
| SCHEMBL6344924 | 0.78 | DRD2 (0.38) | KDM4EHTR2ADRD2TP53LMNA | |
| Bromide SCHEMBL27948604 | 0.76 | HTR2A (0.35) | KDM4EHTR2ADRD2TP53LMNA | |
| SCHEMBL1452158 | 0.76 | HTR2A (0.39) | KDM4EHTR2ADRD2TP53LMNA | |
| SCHEMBL27739315 | 0.76 | CYP11B1 (0.32) | HTR2ATP53CYP11B1CYP11B2 | |
| SCHEMBL18242427 | 0.76 | CYP11B1 (0.32) | HTR2ATP53CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL4660518 | 0.76 | HTR2A (0.39) | KDM4EHTR2ADRD2TP53LMNA | |
| SCHEMBL1453657 | 0.76 | HTR2A (0.40) | KDM4EHTR2ADRD2TP53LMNA | |
| SCHEMBL5668048 | 0.76 | CYP11B1 (0.32) | KDM4EHTR2ATP53CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214948-B1 | PLACING A SOLID PRECURSOR CONTAINING AT LEAST ONE NEUTRAL METALLOCENE DERIVED FROM TRANSITIONAL METAL AND AN IONIZING AGENT, IN CONTACT WITH ORGANOMETALLIC COMPOUND OF 1A, 2A, 2B, 3 AND 4 GROUP | SOLVAY POLYOLEFINS EUROPE-BELGIUM (BE) | 2001-04-10 | — | — | US | disclosed |
| US-5763349-A | Solid precursor of a catalytic system for the polymerization of olefins, process for its preparation, catalytic system comprising this solid precursor and process for the polymerization of olefins in the presence of this catalytic system | SOLVAY POLYOLEFINS EUROPE - BELGIUM (BE) | 1998-06-09 | — | — | US | disclosed |