SCHEMBL7919206

SCHEMBL7919206

CC=[Ti](OC(=O)c1ccc(F)cc1)(OC(=O)c1ccc(F)cc1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.34
NPC1 O15118 5/20 0.34
PKM P14618 2/20 0.34
KMT2A Q03164 6/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
CYP1A2 P05177 2/20 0.33
POLB P06746 2/20 0.33
PLA2G7 Q13093 1/20 0.33
MEN1 O00255 4/20 0.33
HTT P42858 2/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 1/20 0.33
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
ATM Q13315 1/20 0.32
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
TERT O14746 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7924743 0.91 TSHR (0.36) RAB9ANPC1KMT2APLA2G7MEN1
SCHEMBL7924726 0.82 NPC1 (0.35) RAB9ANPC1PKMKMT2ASMN1; SMN2
SCHEMBL7925895 0.82 NPC1 (0.35) RAB9ANPC1PKMKMT2ASMN1; SMN2
SCHEMBL7927789 0.82 POLB (0.34) SMN1; SMN2POLB
SCHEMBL7925761 0.79
SCHEMBL7919211 0.79 RET (0.34) SMN1; SMN2LMNA
SCHEMBL7931023 0.78 PLK1 (0.38) RAB9ANPC1KMT2ASMN1; SMN2CYP1A2
SCHEMBL7924973 0.77 KCNN4 (0.41)
SCHEMBL7924668 0.77 RET (0.33) SMN1; SMN2LMNA
SCHEMBL7919299 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed