SCHEMBL7924743

SCHEMBL7924743

CC=[Ti](OC(=O)c1ccccc1)(OC(=O)c1ccccc1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 3/20 0.34
F2 P00734 1/20 0.34
RAB9A P51151 3/20 0.34
NPC1 O15118 2/20 0.34
ATM Q13315 1/20 0.33
ALDH1A1 P00352 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
HSD17B10 Q99714 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
HSP90AA1 P07900 1/20 0.32
PLA2G7 Q13093 2/20 0.31
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
MAPT P10636 1/20 0.31
CASP3 P42574 1/20 0.31
SENP8 Q96LD8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7919206 0.91 RAB9A (0.34) TSHRKMT2AMEN1LMNARAB9A
SCHEMBL7927789 0.85 POLB (0.34) ALDH1A1TDP1
SCHEMBL7924973 0.82 KCNN4 (0.41)
SCHEMBL7919211 0.82 RET (0.34) LMNA
SCHEMBL7925761 0.82
SCHEMBL7931023 0.81 PLK1 (0.38) KMT2AMEN1LMNARAB9ANPC1
SCHEMBL7927202 0.80 LMNA (0.37) TSHRKMT2AMEN1LMNAF2
SCHEMBL7924668 0.80 RET (0.33) LMNAALDH1A1
SCHEMBL7925640 0.79 TSHR (0.36) TSHRKMT2AMEN1LMNAF2
SCHEMBL7925665 0.76 BRD4 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed