Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921068 | 0.89 | TBXA2R (0.67) | ALDH1A1TBXA2RTBXAS1SGMS1MEN1 | |
| SCHEMBL7918861 | 0.89 | ALDH1A1 (0.63) | ALDH1A1SGMS1MEN1KMT2APKM | |
| SCHEMBL7920702 | 0.88 | ALDH1A1 (0.62) | ALDH1A1TBXA2RTBXAS1SGMS1MEN1 | |
| SCHEMBL7918922 | 0.88 | ALDH1A1 (0.62) | ALDH1A1TBXA2RTBXAS1SGMS1MEN1 | |
| SCHEMBL7919267 | 0.88 | ALDH1A1 (0.65) | ALDH1A1IDO1TBXA2RTBXAS1SGMS1 | |
| SCHEMBL7918986 | 0.88 | ALDH1A1 (0.62) | ALDH1A1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL7918909 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL7918668 | 0.84 | ALDH1A1 (0.54) | ALDH1A1IDO1MEN1KMT2APKM | |
| SCHEMBL7924104 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TBXA2RTBXAS1GAACYP2C9 | |
| SCHEMBL7919257 | 0.82 | ALDH1A1 (0.69) | ALDH1A1IDO1TBXA2RTBXAS1SGMS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811375-B1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA LTD (JP) | 2001-01-03 | — | — | EP | disclosed |
| EP-0811375-A1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA, LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |
| EP-0469901-B1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5189211-A | Thromboxane A2 antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0469901-A1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1992-02-05 | — | — | EP | disclosed |