Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683567 | 0.79 | TSHR (0.50) | TSHRTDP1CYP3A4SMN1; SMN2PKM | |
| SCHEMBL251333 | 0.79 | TSHR (0.48) | TSHRTDP1CYP3A4SMN1; SMN2PKM | |
| SCHEMBL28189920 | 0.75 | TSHR (0.46) | TSHRTDP1CYP3A4SMN1; SMN2PKM | |
| SCHEMBL9486295 | 0.75 | TSHR (0.44) | TSHRTDP1CYP3A4SMN1; SMN2NPSR1 | |
| SCHEMBL16264827 | 0.74 | TSHR (0.47) | TSHRTDP1CYP3A4SMN1; SMN2PKM | |
| SCHEMBL1276382 | 0.74 | TSHR (0.41) | TSHRTDP1CYP3A4SMN1; SMN2PKM | |
| SCHEMBL170670 | 0.72 | TSHR (0.46) | TSHRTDP1CYP3A4SMN1; SMN2PKM | |
| SCHEMBL194711 | 0.72 | — | — | |
| SCHEMBL3840012 | 0.72 | — | — | |
| SCHEMBL16264823 | 0.72 | TSHR (0.42) | TSHRTDP1CYP3A4SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218347-B1 | LATHERING, TEXTURE, FEEL CHARACTERISTICS AND AESTHETICS | THE ANDREW JERGENS COMPANY | 2001-04-17 | — | — | US | disclosed |
| US-6074997-A | NON SOAP | THE ANDREW JERGENS COMPANY (US) | 2000-06-13 | — | — | US | disclosed |
| US-5756438-A | NON-SOAP CLEANSING BAR COMPRISING ANIONIC SURFACTANT, FILLER, AND WAXY BINDER; WEAR RESISTANCE | THE ANDREW JERGENS COMPANY (US) | 1998-05-26 | — | — | US | disclosed |