Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16264827 | 0.87 | TSHR (0.47) | TSHRMEN1POLBKMT2ATDP1 | |
| SCHEMBL27666456 | 0.82 | CA12 (0.37) | TSHRMEN1KMT2ACA12CA1 | |
| SCHEMBL3999882 | 0.82 | TSHR (0.43) | TSHRMEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL6549396 | 0.80 | TSHR (0.42) | TSHRTDP1CYP3A4CA1CA2 | |
| SCHEMBL16264823 | 0.80 | TSHR (0.42) | TSHRTDP1CYP3A4CA1CA2 | |
| SCHEMBL7919563 | 0.79 | TSHR (0.46) | TSHRMEN1POLBKMT2ATDP1 | |
| SCHEMBL28189920 | 0.79 | TSHR (0.46) | TSHRMEN1POLBKMT2ATDP1 | |
| SCHEMBL251333 | 0.79 | TSHR (0.48) | TSHRTDP1CYP3A4CA12CA1 | |
| SCHEMBL28113768 | 0.79 | POLB (0.45) | TSHRMEN1POLBKMT2ATDP1 | |
| SCHEMBL27263131 | 0.79 | OPRK1 (0.37) | TSHRMEN1POLBKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114428-A | Oxidation color dyes with carriers containing soaps, cationic polymers and amines for stabilization | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1992-05-19 | — | — | US | disclosed |