SCHEMBL791971

SCHEMBL791971

COCCc1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.50
CYP2C19 P33261 2/20 0.50
CYP2D6 P10635 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
AKR1B1 P15121 1/20 0.49
NQO2 P16083 1/20 0.49
CYP2C9 P11712 1/20 0.48
ACP3 P15309 1/20 0.47
MTNR1A P48039 2/20 0.46
CDYL Q9Y232 1/20 0.46
IP6K1 Q92551 1/20 0.45
ATM Q13315 1/20 0.45
SLC18A2 Q05940 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30487942 1.00 CYP1A2 (0.50) CYP1A2CYP2C19CYP2D6KDM4EALDH1A1
SCHEMBL2094194 0.89 CYP1A2 (0.47) CYP1A2CYP2C19CYP2D6KDM4EALDH1A1
SCHEMBL5013370 0.87 CYP1A2 (0.46) CYP1A2CYP2C19CYP2D6KDM4EALDH1A1
SCHEMBL2092988 0.85 CYP1A2 (0.44) CYP1A2CYP2C19CYP2D6KDM4EALDH1A1
SCHEMBL586305 0.83 CYP1A2 (0.52) CYP1A2CYP2C19CYP2D6TDP1AKR1B1
SCHEMBL27575466 0.83 HTR2A (0.45) AKR1B1NQO2MTNR1A
SCHEMBL11051055 0.81 CYP1A2 (0.47) CYP1A2CYP2C19CYP2D6KDM4ETDP1
SCHEMBL15669208 0.81 NQO2 (0.50) CYP1A2CYP2C19CYP2D6KDM4EALDH1A1
SCHEMBL7269714 0.80 KDM4E (0.48) CYP1A2CYP2C19CYP2D6KDM4EALDH1A1
SCHEMBL2873340 0.80 TSHR (0.45) KDM4EALDH1A1MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114195611-B Synthesis method of diaryl methane compound 合肥工业大学 2024-05-28 CN disclosed
WO-2022268066-A1 PROTEIN DEGRADATION AGENT 苏州开拓药业股份有限公司 2022-12-29 WO disclosed
CN-114195611-A Synthetic method of diarylmethane compound 合肥工业大学 2022-03-18 CN disclosed
CN-108530365-A 1,4- naphthoquinones/anthraquinone imdazole derivatives and its preparation and use 上海交通大学 2018-09-14 CN disclosed
CN-107561859-A Black photosensitive resin composition and application thereof 奇美实业股份有限公司 2018-01-09 CN disclosed
CN-107463067-A Black photosensitive resin composition and application thereof 奇美实业股份有限公司 2017-12-12 CN disclosed
EP-2884982-B1 SUBSTITUTED PHENYL SPLEEN TYROSINE KINASE (Syk) INHIBITORS MERCK SHARP & DOHME (US) 2017-09-20 EP disclosed
CN-106933032-A Black photosensitive resin composition and application thereof 奇美实业股份有限公司 2017-07-07 CN disclosed
CN-106918994-A Photosensitive resin composition for black matrix and application thereof 奇美实业股份有限公司 2017-07-04 CN disclosed
CN-106406025-A Black photosensitive resin composition and application thereof 奇美实业股份有限公司 2017-02-15 CN disclosed
EP-0795548-B1 QUINAZOLINE DERIVATIVES AND USE THEREOF SUNTORY LTD (JP) 2002-07-03 EP disclosed
EP-1192950-A1 PREVENTIVE OR THERAPEUTIC DRUGS FOR DERMATITISES CONTAINING CHYMASE INHIBITORS AS THE ACTIVE INGREDIENT SUNTORY LIMITED (JP) 2002-04-03 EP disclosed
EP-1171414-A1 COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2002-01-16 EP disclosed
WO-2000063153-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-10-26 WO disclosed
US-5814631-A CHYMASE INHIBITOR, CARDIVASCULAR SUNTORY LIMITED (JP) 1998-09-29 US disclosed
EP-0795548-A1 QUINAZOLINE DERIVATIVES AND USE THEREOF SUNTORY LIMITED (JP) 1997-09-17 EP disclosed
EP-0441383-B1 Use of a copolymer for the making of contact lenses MITSUBISHI RAYON CO (JP) 1996-05-08 EP disclosed
US-5183870-A A curable polybutylene glycol di(meth)acrylate, a urethane or epoxy (meth)acrylate and a (meth)acrylate; heat and water resistance; impact strength; dyeability; workability MITSUBISHI RAYON CO., LTD (JP) 1993-02-02 US disclosed
EP-0441383-A2 Use of a copolymer for the making of contact lenses MITSUBISHI RAYON CO., LTD. (JP) 1991-08-14 EP disclosed
US-4459186-A Electrochemical oxidation of alkyl aromatic compounds UOP INC. (US) 1984-07-10 US disclosed