Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092988 | 0.98 | CYP1A2 (0.44) | CYP1A2CYP2C19CYP2D6AKR1B1SIGMAR1 | |
| SCHEMBL2094194 | 0.95 | CYP1A2 (0.47) | CYP1A2CYP2C19CYP2D6AKR1B1SIGMAR1 | |
| SCHEMBL791971 | 0.87 | CYP1A2 (0.50) | CYP1A2CYP2C19CYP2D6AKR1B1NQO2 | |
| SCHEMBL30487942 | 0.87 | CYP1A2 (0.50) | CYP1A2CYP2C19CYP2D6AKR1B1NQO2 | |
| SCHEMBL9800436 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP2C19CYP2D6SIGMAR1NQO2 | |
| SCHEMBL5013367 | 0.82 | NQO2 (0.45) | CYP1A2CYP2C19CYP2D6SIGMAR1NQO2 | |
| SCHEMBL27645176 | 0.81 | BCHE (0.49) | SIGMAR1CYP2C9MTNR1ACDYL | |
| SCHEMBL2092985 | 0.81 | NQO2 (0.44) | CYP1A2CYP2C19CYP2D6SIGMAR1NQO2 | |
| SCHEMBL5830948 | 0.80 | GPR84 (0.59) | CYP1A2CYP2C19CYP2D6SIGMAR1NQO2 | |
| SCHEMBL460016 | 0.79 | BCHE (0.52) | CYP1A2CYP2C19CYP2D6SIGMAR1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |