Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | VCP | P55072 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | HPRT1 | P00492 | 9/20 | 0.54 |
| ▸ | PNP | P00491 | 7/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EDNRA | P25101 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9651453 | 0.91 | BLM (0.65) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6377806 | 0.89 | BLM (0.72) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6840470 | 0.89 | BLM (0.72) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6835357 | 0.89 | BLM (0.72) | BLMMEN1KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6380553 | 0.88 | BLM (0.71) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11018320 | 0.88 | BLM (0.56) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6835438 | 0.87 | PNP (0.61) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8981399 | 0.87 | PNP (0.61) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6839494 | 0.87 | PDE3A (0.59) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6839490 | 0.87 | PDE3A (0.59) | BLMMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218568-B1 | REACTING 1-ARALKYLOXY-3-HALO-2-PROPANOL WITH METHOXYMETHYL ALKANOATE IN APROTIC SOLVENT IN THE PRESENCE OF A CATALYST TO PRODUCE 1-ARALKYLOXY-3-HALO-2-(ALKANOYLOXY)METHOXYPROPANE AND TREATING THE PRODUCT WITH ALKALI METAL ALKANOATE | SYNTEX (U.S.A.) INC. | 2001-04-17 | — | — | US | disclosed |
| US-6215017-B1 | 1-ARALKYLOXY-3-ACYLOXY-2-(ACYLOXY)METHOXYPROPANE DERIVATIVE; CHEMICAL INTERMEDIATES FOR VIRICIDE GANCICLOVIR | SYNTEX (U.S.A.) INC. | 2001-04-10 | — | — | US | disclosed |
| US-6040446-A | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative | SYNTEX (U.S.A.) INC. (US) | 2000-03-21 | — | — | US | disclosed |