Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 6/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.36 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114901 | 0.94 | P2RY6 (0.51) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL8970584 | 0.92 | P2RY6 (0.39) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL7922091 | 0.89 | P2RY6 (0.45) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL7245844 | 0.89 | P2RY6 (0.47) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL4455104 | 0.89 | P2RY6 (0.47) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL441119 | 0.87 | P2RY6 (0.42) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL7523510 | 0.85 | P2RY6 (0.49) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL2114899 | 0.85 | P2RY6 (0.49) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL2116345 | 0.83 | P2RY6 (0.47) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL7533550 | 0.83 | POLB (0.51) | P2RY6P2RY14NT5EABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242592-B1 | Process for the preparation of 2′-O-alkyl-guanosine, cytidine, and uridine phosphoramidites | ISIS PHARMACEUTICALS, INC. | 2001-06-05 | — | — | US | disclosed |