SCHEMBL7922091

CCCCCCCCCO[C@@H]1[C@H](O)[C@@H](C(O)C(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)O[C@H]1n1ccc(NC(=O)c2ccccc2)nc1=O

nearest known ligand 0.45

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY6	Q15077	6/20	0.45

▸	P2RY14	Q15391	2/20	0.45

▸	NT5E	P21589	1/20	0.45

▸	ABL1	P00519	1/20	0.40

▸	RIN1	Q13671	1/20	0.40

▸	POLB	P06746	1/20	0.39

▸	P2RY2	P41231	4/20	0.37

▸	P2RY4	P51582	3/20	0.37

▸	LMNA	P02545	1/20	0.35

▸	ST6GAL1	P15907	1/20	0.35

▸	ADORA3	P0DMS8	1/20	0.34

▸	IRAK4	Q9NWZ3	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7919968	0.89	P2RY6 (0.48)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL2114901	0.88	P2RY6 (0.51)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL6932379	0.85	P2RY6 (0.50)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL6930742	0.84	P2RY6 (0.51)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL7245844	0.84	P2RY6 (0.47)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL4455104	0.84	P2RY6 (0.47)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL441119	0.81	P2RY6 (0.42)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL8970584	0.81	P2RY6 (0.39)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL6928960	0.80	P2RY6 (0.55)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL6928963	0.80	P2RY6 (0.55)	P2RY6P2RY14NT5EABL1RIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6242592-B1	Process for the preparation of 2′-O-alkyl-guanosine, cytidine, and uridine phosphoramidites	ISIS PHARMACEUTICALS, INC.	2001-06-05	—	—	US	disclosed