Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881543 | 0.96 | HSD17B10 (0.41) | HSD17B10MEN1KMT2ATDP1USP2 | |
| SCHEMBL15253483 | 0.88 | MEN1 (0.61) | HSD17B10MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL6666230 | 0.88 | MEN1 (0.61) | HSD17B10MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL1170204 | 0.86 | HSD17B10 (0.37) | HSD17B10MEN1KMT2ATDP1USP2 | |
| SCHEMBL1006611 | 0.86 | ALDH1A1 (0.43) | HSD17B10MEN1KMT2ATSHRTDP1 | |
| SCHEMBL17148498 | 0.86 | HTT (0.33) | HSD17B10MEN1KMT2AHTT | |
| SCHEMBL18827718 | 0.82 | — | — | |
| SCHEMBL5809530 | 0.82 | ALDH1A1 (0.46) | HSD17B10TSHRTDP1USP2HTT | |
| SCHEMBL28100619 | 0.82 | TSHR (0.52) | HSD17B10MEN1KMT2ATSHRTDP1 | |
| SCHEMBL543942 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083894-A1 | MULTIBINDING INHIBITORS OF HMG-CoA REDUCTASE | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999063994-A9 | MULTIBINDING INHIBITORS OF HMG-CoA REDUCTASE | ADVANCED MEDICINE INC (US) | 2000-07-27 | — | — | WO | disclosed |
| WO-1999063994-A1 | MULTIBINDING INHIBITORS OF HMG-CoA REDUCTASE | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |