Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1317016 | 1.00 | MMP13 (0.84) | MMP13 | |
| SCHEMBL1318449 | 0.91 | MMP13 (0.84) | MMP13 | |
| SCHEMBL15428863 | 0.91 | MMP13 (0.86) | MMP13 | |
| SCHEMBL7905141 | 0.91 | MMP13 (1.00) | MMP13 | |
| SCHEMBL1319911 | 0.90 | MMP13 (0.85) | MMP13 | |
| SCHEMBL1320102 | 0.90 | MMP13 (0.73) | MMP13 | |
| SCHEMBL1316099 | 0.90 | MMP13 (0.84) | MMP13 | |
| SCHEMBL1318389 | 0.89 | MMP13 (1.00) | MMP13 | |
| SCHEMBL1317771 | 0.88 | MMP13 (1.00) | MMP13 | |
| SCHEMBL1318518 | 0.87 | MMP13 (0.80) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056585-A2 | HETEROARYL DIAMIDE COMPOUNDS USEFUL AS MMP-13 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-20 | — | — | WO | disclosed |