SCHEMBL7920121

SCHEMBL7920121

NC(C(=O)O)c1ccccc1F.[NaH]

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.49
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
CNR2 P34972 1/20 0.44
IDO1 P14902 1/20 0.42
TDO2 P48775 1/20 0.42
MEN1 O00255 2/20 0.41
CYP1A2 P05177 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP3A4 P08684 1/20 0.41
KCNN4 O15554 1/20 0.41
GRM1 Q13255 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
DPP4 P27487 1/20 0.39
DPP7 Q9UHL4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15430213 0.98 GAA (0.50) GAACES2CES1CNR2IDO1
SCHEMBL2628067 0.98 GAA (0.50) GAACES2CES1CNR2IDO1
SCHEMBL29557378 0.98 GAA (0.50) GAACES2CES1CNR2IDO1
SCHEMBL27967493 0.98 GAA (0.50) GAACES2CES1CNR2IDO1
Hydrochloric Acid SCHEMBL23886485 0.96 GAA (0.49) GAACES2CES1CNR2IDO1
Hydrochloric Acid SCHEMBL25195986 0.96 GAA (0.49) GAACES2CES1CNR2IDO1
SCHEMBL24044801 0.83 MEN1 (0.48) MEN1CYP1A2KMT2ACYP3A4GRM1
SCHEMBL27966275 0.82 CES2 (0.50) GAACES2CES1CNR2MEN1
Hydrochloric Acid SCHEMBL27841046 0.82 MEN1 (0.41) GAACES2CES1CNR2IDO1
SCHEMBL11214243 0.82 GAA (0.50) GAACES2CES1CNR2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6300517-B1 SUITABLE AS CONSTITUENTS OF METAL COMPLEXES WHICH CAN BE USED AS CATALYSTS FOR REACTIONS TO FORM C--C, C--H, C--N, C--SI OR C--O BONDS CELANESE GMBH (DE) 2001-10-09 US disclosed