SCHEMBL7920249

SCHEMBL7920249

CCO[Si](CCc1cccc(OC#N)c1)(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACHE P22303 8/20 0.36
TAAR1 Q96RJ0 1/20 0.36
RAB9A P51151 1/20 0.35
CHRM2 P08172 2/20 0.35
CHRM1 P11229 2/20 0.35
CHRM3 P20309 2/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913967 0.92 MTNR1A (0.38) ACHETAAR1CHRM2CHRM1CHRM3
SCHEMBL7915041 0.85 TAAR1 (0.45) TAAR1RAB9ACHRM2CHRM1CHRM3
SCHEMBL15672359 0.82 TAAR1 (0.56) TAAR1CHRM2CHRM1CHRM3MTNR1A
SCHEMBL7914003 0.82 ACACB (0.32) TAAR1KMT2A
SCHEMBL574686 0.81 CYP4F2 (0.38) ACHETAAR1CHRM2CHRM1CHRM3
SCHEMBL7906836 0.79 MEN1 (0.38) ACHETAAR1RAB9ACHRM2CHRM1
SCHEMBL7913932 0.77 CHRM2 (0.44) TAAR1RAB9ACHRM2CHRM1CHRM3
SCHEMBL29564713 0.75 TAAR1 (0.50) TAAR1RAB9ACYP4F2CYP4A11
SCHEMBL15672382 0.75 TAAR1 (0.50) TAAR1RAB9ACYP4F2CYP4A11
SCHEMBL8603014 0.75 TAAR1 (0.40) ACHETAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6217943-B1 ADHESION AND REINFORCEMENT WITH SILANE CYANATE COUPLERS 3M INNOVATIVE PROPERTIES COMPANY 2001-04-17 US disclosed
US-5912377-A CONTAINING AT LEAST ONE CYANATE ESTER GROUP AND HYDROLYZABLE SILYL GROUP; REINFORCED COMPOSITES, ADESIVES, COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-15 US disclosed
EP-0830410-B1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING & MFG (US) 1999-04-07 EP disclosed
EP-0830410-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-25 EP disclosed
WO-1996039457-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-12 WO disclosed