Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7927682 | 1.00 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7924554 | 0.85 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7925882 | 0.85 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7916694 | 0.85 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7926870 | 0.83 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL7918284 | 0.83 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL7916818 | 0.83 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL7924617 | 0.83 | CYP11B1 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL7929235 | 0.81 | CYP11B1 (0.34) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7926443 | 0.79 | ADRA2A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042473-A1 | BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |