Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789445 | 0.88 | GRM2 (0.32) | GRM2GRM5GRM1 | |
| SCHEMBL1952301 | 0.88 | GRM2 (0.32) | GRM2GRM5GRM1 | |
| SCHEMBL5692521 | 0.88 | GRM2 (0.32) | GRM2GRM5GRM1 | |
| SCHEMBL13336901 | 0.88 | GRM2 (0.32) | GRM2GRM5GRM1 | |
| SCHEMBL13336913 | 0.88 | GRM2 (0.32) | GRM2GRM5GRM1 | |
| SCHEMBL15893770 | 0.88 | GRM2 (0.32) | GRM2GRM5GRM1 | |
| Hydrochloric Acid SCHEMBL1071123 | 0.87 | GRM2 (0.31) | GRM2GRM5GRM1 | |
| SCHEMBL15423558 | 0.87 | GRM2 (0.31) | GRM2GRM5GRM1 | |
| Hydrochloric Acid SCHEMBL4562827 | 0.87 | GRM2 (0.31) | GRM2GRM5GRM1 | |
| Hydrochloric Acid SCHEMBL4777044 | 0.87 | GRM2 (0.31) | GRM2GRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331552-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2013-02-27 | — | — | EP | disclosed |
| WO-2010036551-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-04-01 | — | — | WO | disclosed |
| US-20100080770-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100080770-A1 | Hepatitis C Virus Inhibitors | HAVCR2, HCCS, PYGL | SCN9A 4339/4885GRM2 4310/4885GRM5 3534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.