Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.46 |
| ▸ | FABP7 | O15540 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920816 | 1.00 | KMT2A (0.46) | KMT2AFABP5FABP7TSHREPHX2 | |
| SCHEMBL7926629 | 0.86 | KMT2A (0.46) | KMT2AFABP5FABP7TSHREPHX2 | |
| SCHEMBL6855032 | 0.86 | KMT2A (0.46) | KMT2AFABP5FABP7TSHREPHX2 | |
| SCHEMBL12292636 | 0.85 | FABP5 (0.45) | KMT2AFABP5FABP7TSHREPHX2 | |
| SCHEMBL119453 | 0.85 | FABP5 (0.52) | KMT2AFABP5FABP7TSHREPHX2 | |
| SCHEMBL28891959 | 0.83 | KMT2A (0.46) | KMT2AFABP5FABP7TSHREPHX2 | |
| SCHEMBL14438582 | 0.83 | KMT2A (0.43) | KMT2AFABP5FABP7TSHREPHX2 | |
| SCHEMBL12292634 | 0.83 | KMT2A (0.43) | KMT2AFABP5FABP7TSHREPHX2 | |
| SCHEMBL6375144 | 0.82 | FABP5 (0.53) | KMT2AFABP5FABP7TSHREPHX2 | |
| SCHEMBL30422339 | 0.82 | KMT2A (0.43) | KMT2AFABP5FABP7TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184389-B1 | FEATURE A PLURALITY OF FUNCTIONAL GROUPS ATTACHED TO BACKBONE AND PHOSPHORAMIDATE SITES | ISIS PHARMACEUTICALS, INC. | 2001-02-06 | — | — | US | disclosed |