SCHEMBL6375144

SCHEMBL6375144

O=C(OCC1c2ccccc2-c2ccccc21)N1CC(c2ccccc2)C1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.53
FABP7 O15540 2/20 0.53
KMT2A Q03164 3/20 0.45
F10 P00742 2/20 0.44
EPHX2 P34913 1/20 0.42
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
PRMT5 O14744 3/20 0.40
WDR77 Q9BQA1 3/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
TSHR P16473 1/20 0.40
DPP8 Q6V1X1 1/20 0.40
DPP9 Q86TI2 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119453 0.86 FABP5 (0.52) FABP5FABP7KMT2AF10EPHX2
SCHEMBL4709998 0.85 FABP5 (0.49) FABP5FABP7KMT2AF10EPHX2
SCHEMBL24967824 0.83 FABP5 (0.51) FABP5FABP7KMT2AF10EPHX2
SCHEMBL30824716 0.82 TSHR (0.50) FABP5FABP7KMT2AEPHX2ALDH1A1
SCHEMBL8222797 0.82 TSHR (0.50) FABP5FABP7KMT2AEPHX2ALDH1A1
SCHEMBL30555288 0.82 TSHR (0.50) FABP5FABP7KMT2AEPHX2ALDH1A1
SCHEMBL7920813 0.82 KMT2A (0.46) FABP5FABP7KMT2AF10EPHX2
SCHEMBL7920816 0.82 KMT2A (0.46) FABP5FABP7KMT2AF10EPHX2
SCHEMBL29341819 0.82 FABP5 (0.55) FABP5FABP7KMT2AF10EPHX2
SCHEMBL22397770 0.82 POLB (0.52) FABP5FABP7KMT2AEPHX2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6936586-B1 Synthetic IL-10 analogues STEENO RESEARCH GROUP A/S (DK) 2005-08-30 US disclosed