Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924095 | 0.91 | ALDH1A1 (0.62) | ALDH1A1GAAHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL7920706 | 0.90 | ALDH1A1 (0.53) | ALDH1A1GAAHSD17B10CYP3A4TSHR | |
| SCHEMBL7911840 | 0.90 | ALDH1A1 (0.62) | ALDH1A1GAAHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL7918672 | 0.90 | ALDH1A1 (0.50) | ALDH1A1GAAHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL7924028 | 0.90 | ALDH1A1 (0.62) | ALDH1A1GAAHSD17B10CYP3A4TSHR | |
| SCHEMBL7918975 | 0.87 | ALDH1A1 (0.47) | ALDH1A1GAAHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL7919302 | 0.84 | ALDH1A1 (0.58) | ALDH1A1GAAHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL7924132 | 0.84 | ALDH1A1 (0.55) | ALDH1A1GAAHSD17B10NFKB1TSHR | |
| SCHEMBL7918943 | 0.82 | ALDH1A1 (0.52) | ALDH1A1GAAHSD17B10TSHRMAPT | |
| SCHEMBL7911874 | 0.81 | ALDH1A1 (0.62) | ALDH1A1GAAHSD17B10CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811375-B1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA LTD (JP) | 2001-01-03 | — | — | EP | disclosed |
| EP-0811375-A1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA, LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |
| EP-0469901-B1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5189211-A | Thromboxane A2 antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0469901-A1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1992-02-05 | — | — | EP | disclosed |