Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.57 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.56 |
| ▸ | GBA1 | P04062 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920954 | 1.00 | S1PR5 (0.57) | S1PR5S1PR1FUCA1GBA1GRIN2B | |
| SCHEMBL7920949 | 1.00 | S1PR5 (0.57) | S1PR5S1PR1FUCA1GBA1GRIN2B | |
| SCHEMBL879296 | 0.84 | S1PR5 (0.46) | S1PR5S1PR1FUCA1GBA1GRIN2B | |
| SCHEMBL19023808 | 0.83 | S1PR5 (0.54) | S1PR5S1PR1FUCA1GBA1GRIN2B | |
| SCHEMBL20875290 | 0.83 | S1PR5 (0.54) | S1PR5S1PR1FUCA1GBA1GRIN2B | |
| SCHEMBL19023811 | 0.83 | S1PR5 (0.54) | S1PR5S1PR1FUCA1GBA1GRIN2B | |
| SCHEMBL19023812 | 0.83 | S1PR5 (0.54) | S1PR5S1PR1FUCA1GBA1GRIN2B | |
| SCHEMBL7148453 | 0.80 | S1PR5 (0.51) | S1PR5S1PR1FUCA1GRIN2B | |
| SCHEMBL14759418 | 0.79 | GBA1 (0.75) | S1PR5S1PR1FUCA1GBA1SIGMAR1 | |
| SCHEMBL742926 | 0.79 | GBA1 (0.75) | S1PR5S1PR1FUCA1GBA1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184389-B1 | FEATURE A PLURALITY OF FUNCTIONAL GROUPS ATTACHED TO BACKBONE AND PHOSPHORAMIDATE SITES | ISIS PHARMACEUTICALS, INC. | 2001-02-06 | — | — | US | disclosed |