Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593156 | 0.90 | GPBAR1 (0.52) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL1695520 | 0.83 | CYSLTR1 (0.50) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL9844656 | 0.80 | CYSLTR1 (0.55) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL7504609 | 0.77 | CYSLTR1 (0.55) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL28015630 | 0.76 | GPBAR1 (0.55) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL6740564 | 0.76 | KMT2A (0.51) | CYP1A2ALOX5 | |
| SCHEMBL19385993 | 0.74 | CYSLTR1 (0.46) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL19385992 | 0.74 | CYSLTR1 (0.46) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL8557157 | 0.73 | CYP1A2 (0.51) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| Acetic Acid SCHEMBL3951221 | 0.73 | GPBAR1 (0.58) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530639-B1 | Quinolylmethoxy-phenylacetamides substituted by a heterocycle as lipoxygenase inhibitors | BAYER AG (DE) | 1994-08-17 | — | — | EP | claimed |
| US-5310744-A | Antiinflammatory | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-10 | — | — | US | claimed |
| US-5266578-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | claimed |
| CN-1070190-A | The quinolylmethoxy-phenylacetamides of heterocyclic substituted | BAYER AG (DE) | 1993-03-24 | — | — | CN | claimed |
| JP-5194403-A | — | — | None | — | — | JP | disclosed |
| US-6277833-B1 | 3-HYDROXY-3-METHYL-GLUTARYL COENZYME A (HGM--COA) REDUCTASE INHIBITORS WHICH RETARD CHOLESTEROL BIOSYNTHESIS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-21 | — | — | US | disclosed |
| US-5861385-A | Substituted triols | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | disclosed |
| EP-0530639-B1 | Quinolylmethoxy-phenylacetamides substituted by a heterocycle as lipoxygenase inhibitors | BAYER AG (DE) | 1994-08-17 | — | — | EP | disclosed |
| US-5310744-A | Antiinflammatory | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5310744-A | Antiinflammatory | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5310744-A | Antiinflammatory | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5266578-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |
| US-5266578-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |
| JP-H05194403-A | HETEROCYCLICALLY SUBSTITUTED QUINOLYMETHOXY-PHENYLACETAMIDE | BAYER AG | 1993-08-03 | — | — | JP | disclosed |
| EP-0545170-A1 | Quinolylmethoxyphenylacetamides | BAYER AG (DE) | 1993-06-09 | — | — | EP | disclosed |
| CN-1070190-A | The quinolylmethoxy-phenylacetamides of heterocyclic substituted | BAYER AG (DE) | 1993-03-24 | — | — | CN | disclosed |
| CN-1070190-A | The quinolylmethoxy-phenylacetamides of heterocyclic substituted | BAYER AG (DE) | 1993-03-24 | — | — | CN | disclosed |
| CN-1070190-A | The quinolylmethoxy-phenylacetamides of heterocyclic substituted | BAYER AG (DE) | 1993-03-24 | — | — | CN | disclosed |
| EP-0530639-A1 | Quinolylmethoxy-phenylacetamides substituted by a heterocycle as lipoxygenase inhibitors | BAYER AG (DE) | 1993-03-10 | — | — | EP | disclosed |
| EP-0530639-A1 | Quinolylmethoxy-phenylacetamides substituted by a heterocycle as lipoxygenase inhibitors | BAYER AG (DE) | 1993-03-10 | — | — | EP | disclosed |