Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.55 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7504609 | 0.81 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2GPBAR1MAPK1TP53 | |
| SCHEMBL7921077 | 0.80 | GPBAR1 (0.51) | CYSLTR1CYSLTR2GPBAR1CYP1A2ALOX5 | |
| SCHEMBL7593156 | 0.78 | GPBAR1 (0.52) | CYSLTR1CYSLTR2GPBAR1CYP1A2ALOX5 | |
| SCHEMBL12530278 | 0.77 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2GPBAR1CYP1A2PDE10A | |
| SCHEMBL19407459 | 0.76 | GRIN2D (0.53) | CYSLTR1CYSLTR2GPBAR1CYP1A2 | |
| SCHEMBL1715309 | 0.74 | CYSLTR1 (0.62) | CYSLTR1CYSLTR2GPBAR1PDE10AFFAR1 | |
| SCHEMBL2353460 | 0.74 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2GPBAR1PDE10AFFAR1 | |
| SCHEMBL31570744 | 0.73 | CYSLTR2 (0.51) | CYSLTR1CYSLTR2GPBAR1CYP1A2ALDH1A1 | |
| SCHEMBL31570746 | 0.73 | CYSLTR2 (0.51) | CYSLTR1CYSLTR2GPBAR1CYP1A2ALDH1A1 | |
| SCHEMBL1695520 | 0.72 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1CYP1A2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414019-A2 | Subsituted N-(quinolin-2-yl-methoxy)benzylsulfonylureas | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |