Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243843 | 0.83 | KMT2A (0.42) | KMT2AMEN1CYP2C19PRSS1KDM4E | |
| SCHEMBL8569592 | 0.81 | CDK5 (0.53) | KMT2AMEN1NAPRTKDM4EALDH1A1 | |
| SCHEMBL3243431 | 0.74 | KMT2A (0.69) | KMT2APRSS1 | |
| SCHEMBL3245441 | 0.73 | KMT2A (0.50) | KMT2APRSS1 | |
| SCHEMBL4851229 | 0.72 | NAPRT (0.67) | KMT2AMEN1NAPRTMAPK14KDM4E | |
| SCHEMBL30114893 | 0.72 | NAPRT (0.67) | KMT2AMEN1NAPRTMAPK14KDM4E | |
| SCHEMBL28693694 | 0.71 | KMT2A (0.69) | KMT2APRSS1 | |
| SCHEMBL3248740 | 0.71 | MRGPRX4 (0.56) | KMT2ACYP2C19ALDH1A1MAPT | |
| SCHEMBL8198020 | 0.70 | NAPRT (0.73) | NAPRTKDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL3243548 | 0.70 | PPARG (0.41) | KMT2AMEN1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056195-A1 | NEW COMPOUNDS 575 | ASTRAZENECA AB (SE) | 2010-05-20 | — | — | WO | disclosed |