Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4614749 | 0.82 | MEN1 (0.39) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL7760837 | 0.80 | MEN1 (0.38) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL4586849 | 0.78 | MEN1 (0.37) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL10086063 | 0.76 | — | — | |
| SCHEMBL4613684 | 0.73 | MAPT (0.34) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| Anthracene SCHEMBL28886884 | 0.73 | RPS6KB2 (0.46) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL3061563 | 0.73 | MEN1 (0.33) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL992407 | 0.72 | ALDH1A1 (0.36) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL4149778 | 0.72 | MAPT (0.33) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL723960 | 0.71 | CYP2A6 (0.44) | MEN1KMT2ARAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274590-B1 | ADMINISTERING 3,4-DIARYLTHIOPHENE DERIVATIVE TO TREAT ECZEMA, BURNS, PSORIASIS, AND DERMATITIS | G. D. SEARLE & CO. | 2001-08-14 | — | — | US | disclosed |