Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 14/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1390601 | 1.00 | RORC (0.42) | RORCCXCR2DRD2HTR1DDRD3 | |
| SCHEMBL1390545 | 1.00 | RORC (0.42) | RORCCXCR2DRD2HTR1DDRD3 | |
| SCHEMBL1390598 | 1.00 | RORC (0.42) | RORCCXCR2DRD2HTR1DDRD3 | |
| SCHEMBL1390540 | 1.00 | RORC (0.42) | RORCCXCR2DRD2HTR1DDRD3 | |
| SCHEMBL1390922 | 1.00 | RORC (0.42) | RORCCXCR2DRD2HTR1DDRD3 | |
| SCHEMBL1390942 | 1.00 | RORC (0.42) | RORCCXCR2DRD2HTR1DDRD3 | |
| SCHEMBL1390693 | 0.77 | MAPT (0.41) | — | |
| SCHEMBL1390878 | 0.77 | MAPT (0.41) | — | |
| SCHEMBL7795628 | 0.77 | CXCR2 (0.39) | CXCR2DRD2HTR1DDRD3HSD11B1 | |
| SCHEMBL7922873 | 0.74 | ACACB (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050445-A1 | BICYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |