Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19827872 | 0.85 | ACHE (0.41) | ACHESTING1 | |
| SCHEMBL21136248 | 0.85 | ACHE (0.36) | ACHEKDM4ECDK5CDK5R1FGFR1 | |
| SCHEMBL18061768 | 0.85 | ACHE (0.36) | ACHEKDM4ECDK5CDK5R1FGFR1 | |
| SCHEMBL26780401 | 0.85 | ACHE (0.36) | ACHEKDM4ECDK5CDK5R1FGFR1 | |
| SCHEMBL18061767 | 0.85 | ACHE (0.41) | ACHESTING1 | |
| SCHEMBL8668421 | 0.84 | NT5E (0.36) | STING1 | |
| SCHEMBL18061764 | 0.81 | ACHE (0.37) | ACHEKDM4ECDK5CDK5R1 | |
| SCHEMBL30534045 | 0.80 | ACHE (0.33) | ACHE | |
| SCHEMBL21136249 | 0.80 | ACHE (0.33) | ACHE | |
| SCHEMBL18061770 | 0.80 | ACHE (0.33) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232463-B1 | CROSSLINKING OLIGONUCLEOTIDES CONTAINING PURINE ANALOGS HAVING REACTIVE SITES ON THE NUCLEOBASE AND ON A SUGAR MOIETY; ANTISENSE AGENTS | ISIS PHARMACEUTICALS, INC. | 2001-05-15 | — | — | US | disclosed |