Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448375 | 0.91 | LMNA (0.47) | MEN1KMT2AATMKCNH2CHRM2 | |
| SCHEMBL7921443 | 0.88 | ATM (0.45) | MEN1KMT2AATMCYP3A4KCNH2 | |
| Hydrochloric Acid SCHEMBL7921978 | 0.87 | MEN1 (0.44) | MEN1KMT2AATMCYP3A4KCNH2 | |
| SCHEMBL7436136 | 0.86 | LMNA (0.46) | MEN1KMT2AATMKCNH2CHRM2 | |
| SCHEMBL7442593 | 0.82 | MEN1 (0.43) | MEN1KMT2AATMCYP3A4KCNH2 | |
| SCHEMBL7446880 | 0.82 | LMNA (0.46) | MEN1KMT2AATMKCNH2CHRM2 | |
| SCHEMBL7921863 | 0.81 | TACR1 (0.41) | MEN1KMT2AATMALDH1A1 | |
| SCHEMBL195024 | 0.80 | LMNA (0.48) | MEN1KMT2AATMKCNH2CHRM2 | |
| SCHEMBL7444990 | 0.80 | LMNA (0.48) | MEN1KMT2AATMCYP3A4KCNH2 | |
| SCHEMBL7442393 | 0.80 | LMNA (0.48) | MEN1KMT2AATMKCNH2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |