SCHEMBL792197

SCHEMBL792197

COc1ccc(-c2cccc(OC)c2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 3/20 0.77
ABCB1 P08183 3/20 0.77
BCR P11274 3/20 0.77
MAOB P27338 2/20 0.62
CYP1A1 P04798 1/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2E1 P05181 1/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2C8 P10632 1/20 0.61
CYP2D6 P10635 1/20 0.61
CYP2A6 P11509 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP4B1 P13584 1/20 0.61
CYP2B6 P20813 1/20 0.61
CYP3A5 P20815 1/20 0.61
CYP2A7 P20853 1/20 0.61
CYP3A7 P24462 1/20 0.61
CYP2F1 P24903 1/20 0.61
CYP2C18 P33260 1/20 0.61
CYP2C19 P33261 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1180412 1.00 ABL1 (0.77) ABL1ABCB1BCRMAOBCYP1A1
SCHEMBL1181204 0.98 ABL1 (0.81) ABL1ABCB1BCRMAOBCYP1A1
SCHEMBL1180343 0.95 ABL1 (0.69) ABL1ABCB1BCRMAOBCYP1A1
SCHEMBL9414212 0.91 ABL1 (0.66) ABL1ABCB1BCRMAOBCYP1A1
SCHEMBL13247865 0.91 ABL1 (0.64) ABL1ABCB1BCRMAOBCYP1A1
SCHEMBL1180429 0.91 ABL1 (0.83) ABL1ABCB1BCRCYP1A1CYP1A2
SCHEMBL196765 0.91 CYP3A4 (0.73) ABL1ABCB1BCRMAOBCYP1A1
SCHEMBL29489425 0.91 CYP3A4 (0.73) ABL1ABCB1BCRMAOBCYP1A1
SCHEMBL29740761 0.88 CYP1A1 (0.64) ABL1ABCB1BCRMAOBCYP1A1
SCHEMBL458391 0.88 CYP1A1 (0.64) ABL1ABCB1BCRMAOBCYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011132194-A1 PROCESS FOR THE PREPARATION OF RALOXIFENE HYDROCHLORIDE HETERO RESEARCH FOUNDATION (IN) 2011-10-27 WO claimed
WO-1999025707-A1 2-ARYLBENZO[b]THIOPHENES USEFUL FOR THE TREATMENT OF ESTROGEN DEPRIVATION SYNDROME ELI LILLY AND COMPANY (US) 1999-05-27 WO claimed
WO-1999007693-A1 BENZOTHIOPHENES ELI LILLY AND COMPANY (US) 1999-02-18 WO claimed
US-20230399460-A1 Liquid Crystalline Polyesters (LCP) and Thermoplastic Compositions having Low Dielectric Constant (Dk) and Dissipation Factor (Df) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-12-14 US disclosed
US-20230399460-A1 Liquid Crystalline Polyesters (LCP) and Thermoplastic Compositions having Low Dielectric Constant (Dk) and Dissipation Factor (Df) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-12-14 US disclosed
WO-2023185162-A1 INSULATOR FOR BATTERIES SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-10-05 WO disclosed
CN-104016898-B 3,4-disubstituted pyrroles compounds and its preparation method and application 上海交通大学 2016-07-06 CN disclosed
EP-2287141-B1 METHOD FOR PRODUCING UNSATURATED ORGANIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-10-21 EP disclosed
US-8394468-B2 Polymerizable compound and liquid crystal composition including it JNC CORPORATION (JP) 2013-03-12 US disclosed
US-8394468-B2 Polymerizable compound and liquid crystal composition including it JNC CORPORATION (JP) 2013-03-12 US disclosed
US-8237002-B2 Method for producing unsaturated organic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-07 US disclosed
WO-1996040693-A1 PROCESS FOR THE SYNTHESIS OF VINYL SULFENIC ACID DERIVATIVES ELI LILLY AND COMPANY (US) 1996-12-19 WO disclosed
WO-1996040678-A1 PROCESS FOR THE SYNTHESIS OF BENZO[b]THIOPHENES ELI LILLY AND COMPANY (US) 1996-12-19 WO disclosed
WO-1996040676-A1 PROCESS FOR THE SYNTHESIS OF BENZO[b]THIOPHENES ELI LILLY AND COMPANY (US) 1996-12-19 WO disclosed
WO-1996040691-A1 VINYL SULFOXIDES AND A PROCESS FOR THEIR SYNTHESIS ELI LILLY AND COMPANY (US) 1996-12-19 WO disclosed
US-5514703-A INTERRUPTION OF LEUKOTRIENE PATHWAY ELI LILLY AND COMPANY (US) 1996-05-07 US disclosed
US-5514704-A AND LIPOXYGENASE ELI LILLY AND COMPANY (US) 1996-05-07 US disclosed
US-5512684-A Process for preparing 3-(4-aminoethoxy-benzoyl) benzo B!-thiophenes ELI LILLY AND COMPANY (US) 1996-04-30 US disclosed
WO-1996002248-A1 CANNABINOID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-02-01 WO disclosed
EP-0675121-A1 Novel intermediates and processes for preparing benzothiophene compounds ELI LILLY AND COMPANY (US) 1995-10-04 EP disclosed