Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9459439 | 0.92 | CHRM2 (0.48) | CHRM2CHRM1 | |
| SCHEMBL7913911 | 0.90 | CHRM2 (0.44) | CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL9442633 | 0.90 | CHRM2 (0.47) | CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL9459064 | 0.89 | CHRM2 (0.43) | CHRM2CHRM1 | |
| SCHEMBL9293807 | 0.77 | CHRM2 (0.39) | CHRM2 | |
| SCHEMBL9584936 | 0.75 | CHRM2 (0.41) | CHRM2CHRM1 | |
| SCHEMBL9459002 | 0.74 | CHRM2 (0.40) | CHRM2CHRM1 | |
| SCHEMBL9458858 | 0.74 | CHRM2 (0.47) | CHRM2 | |
| SCHEMBL9459083 | 0.71 | CHRM1 (0.42) | CHRM2CHRM1 | |
| SCHEMBL9458919 | 0.71 | CHRM2 (0.40) | CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327155-A2 | Pyrazines, pyrimidines and pyridazines, useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-08-09 | — | — | EP | claimed |
| EP-0871445-A4 | COMPOSITION FOR TREATING PAIN | LILLY CO ELI (US) | 2001-01-10 | — | — | EP | disclosed |
| EP-0783304-A4 | METHOD FOR TREATING ANXIETY | LILLY CO ELI (US) | 1999-01-27 | — | — | EP | disclosed |
| EP-0871445-A1 | COMPOSITION FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| EP-0783304-A1 | METHOD FOR TREATING ANXIETY | ELI LILLY AND COMPANY (US) | 1997-07-16 | — | — | EP | disclosed |
| WO-1997020561-A1 | COMPOSITION FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 1997-06-12 | — | — | WO | disclosed |
| US-5574053-A | Method for treating anxiety | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5574029-A | Method for treating anxiety | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5574028-A | SEDATIVES | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| WO-1996013261-A1 | METHOD FOR TREATING ANXIETY | ELI LILLY AND COMPANY (US) | 1996-05-09 | — | — | WO | disclosed |
| US-5260293-A | Simulate central muscarinic acetlycholine receptors | MERCK SHARP & DOHME LIMITED (GB) | 1993-11-09 | — | — | US | disclosed |
| EP-0327155-A2 | Pyrazines, pyrimidines and pyridazines, useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-08-09 | — | — | EP | disclosed |