Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140885 | 0.85 | ADORA2A (0.53) | ADORA2AADORA1SLC2A1MAPTALDH1A1 | |
| SCHEMBL8381283 | 0.83 | ADORA2A (0.57) | ADORA2AADORA1SLC2A1MAPTALDH1A1 | |
| SCHEMBL13222014 | 0.83 | ADORA2A (0.53) | ADORA2AADORA1SLC2A1MAPTALDH1A1 | |
| SCHEMBL12192256 | 0.82 | TRPM8 (0.56) | ADORA2AADORA1SLC2A1MAPTALDH1A1 | |
| SCHEMBL14012815 | 0.80 | KRAS (0.45) | ADORA2AADORA1MAPTALDH1A1POLB | |
| SCHEMBL577737 | 0.78 | ADORA1 (0.53) | ADORA2AADORA1SLC2A1MAPTALDH1A1 | |
| SCHEMBL15692154 | 0.78 | ADORA2A (0.57) | ADORA2AADORA1SLC2A1MAPTALDH1A1 | |
| SCHEMBL4740163 | 0.76 | METAP1 (0.60) | ADORA2AADORA1SLC2A1MAPTALDH1A1 | |
| SCHEMBL577738 | 0.75 | ADORA2A (0.53) | ADORA2AADORA1SLC2A1MAPTALDH1A1 | |
| SCHEMBL20665356 | 0.75 | ADORA1 (0.53) | ADORA2AADORA1SLC2A1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287449-A1 | AZA-TRIPEPTIDE HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2008-11-20 | — | — | US | disclosed |
| US-20080267917-A1 | N-FUNCTIONALIZED AMIDES AS HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2008-10-30 | — | — | US | disclosed |
| US-20080267917-A1 | N-FUNCTIONALIZED AMIDES AS HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267917-A1 | N-FUNCTIONALIZED AMIDES AS HEPATITIS C SERINE PROTEASE INHIBITORS | PRSS1, HPN, SPINT2 | ADORA2A 2525/4885ADORA1 2538/4885SLC2A1 2255/4885 |
| US-20080287449-A1 | AZA-TRIPEPTIDE HEPATITIS C SERINE PROTEASE INHIBITORS | CTSC, DPP4, ANPEP | ADORA2A 3049/4885ADORA1 3007/4885SLC2A1 2579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.