Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 3/20 | 0.50 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.50 |
| ▸ | PTGFR | P43088 | 2/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | PTGIR | P43119 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922152 | 1.00 | PTGER3 (0.50) | PTGER3PTGDRTBXA2RPTGER4PTGFR | |
| SCHEMBL7922214 | 0.77 | PTGER3 (0.63) | PTGER3PTGER4PTGER2HDAC3HDAC1 | |
| SCHEMBL7922217 | 0.77 | PTGER3 (0.63) | PTGER3PTGER4PTGER2HDAC3HDAC1 | |
| SCHEMBL7712681 | 0.77 | HDAC1 (0.78) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9033657 | 0.77 | HDAC1 (0.78) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9584191 | 0.76 | APP (0.53) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9034832 | 0.76 | HDAC8 (0.56) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7818354 | 0.72 | PTGER3 (0.50) | PTGER3PTGDRTBXA2RPTGER4PTGFR | |
| SCHEMBL7818358 | 0.72 | PTGER3 (0.50) | PTGER3PTGDRTBXA2RPTGER4PTGFR | |
| SCHEMBL8388266 | 0.72 | BACE1 (0.74) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242493-B1 | PROSTAGLANDIN INHIBITORS; ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-06-05 | — | — | US | disclosed |