Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 12/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 11/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9913123 | 1.00 | DRD2 (0.35) | DRD2BACE1BACE2ALDH1A1GAA | |
| SCHEMBL9913133 | 0.94 | DRD2 (0.35) | DRD2BACE1BACE2ALDH1A1GAA | |
| SCHEMBL9913132 | 0.94 | DRD2 (0.35) | DRD2BACE1BACE2ALDH1A1GAA | |
| SCHEMBL7925298 | 0.94 | DRD2 (0.35) | DRD2BACE1BACE2ALDH1A1GAA | |
| SCHEMBL9913143 | 0.92 | BACE1 (0.35) | DRD2BACE1BACE2ALDH1A1GAA | |
| SCHEMBL7916603 | 0.92 | BACE1 (0.35) | DRD2BACE1BACE2ALDH1A1GAA | |
| SCHEMBL8030093 | 0.90 | BACE1 (0.44) | DRD2BACE1BACE2ALDH1A1GAA | |
| SCHEMBL13009269 | 0.90 | BACE1 (0.44) | DRD2BACE1BACE2ALDH1A1GAA | |
| SCHEMBL2632338 | 0.88 | BACE1 (0.45) | DRD2BACE1BACE2ALDH1A1GAA | |
| SCHEMBL10288946 | 0.88 | BACE1 (0.45) | DRD2BACE1BACE2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038686-A1 | NOVEL FUSED AMINODIHYDROTHIAZINE DERIVATIVE | エーザイ・アール・アンド・ディー・マネジメント株式会社 (JP) | 2010-04-08 | — | — | WO | disclosed |