⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL31396433 | 0.91 | — | — | |
| Pyridine SCHEMBL6933426 | 0.88 | TSHR (0.69) | — | |
| Pyridine SCHEMBL27692838 | 0.87 | — | — | |
| Benzene SCHEMBL10751789 | 0.87 | TSHR (1.00) | — | |
| Pyridine SCHEMBL16 | 0.87 | — | — | |
| SCHEMBL3052767 | 0.87 | TSHR (1.00) | — | |
| Pyridine SCHEMBL9037865 | 0.87 | TSHR (1.00) | — | |
| Benzene SCHEMBL1261317 | 0.87 | TSHR (1.00) | — | |
| Pyridine SCHEMBL933604 | 0.87 | TSHR (1.00) | — | |
| Pyridine SCHEMBL180431 | 0.87 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12577267-B2 | Pyrimidine compounds for use as MAP4K1 inhibitors | GLENMARK SPECIALITY S.A. (CH) | 2026-03-17 | — | — | US | disclosed |
| US-20250289830-A1 | KRAS INHIBITORS | ELI LILLY AND COMPANY | 2025-09-18 | — | — | US | disclosed |
| US-12351591-B2 | KRas inhibitors | ELI LILLY AND COMPANY (US) | 2025-07-08 | — | — | US | disclosed |
| EP-4574210-A2 | KAPPA OPIOID RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO | The Scripps Research Institute (US) | 2025-06-25 | — | — | EP | disclosed |
| EP-4141001-B1 | KAPPA OPIOID RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO | SCRIPPS RESEARCH INST (US) | 2025-03-05 | — | — | EP | disclosed |
| EP-4499233-A1 | KRAS INHIBITORS | Eli Lilly and Company (US) | 2025-02-05 | — | — | EP | disclosed |
| CN-119095853-A | KRAS inhibitors | 伊莱利利公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-119039220-A | Synthesis method of chloroquine | 上海应用技术大学 | 2024-11-29 | — | — | CN | disclosed |
| CN-118852002-A | Synthesis method of piperaquine | 上海应用技术大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-118834167-A | Synthesis method of hydroxychloroquine | 上海应用技术大学 | 2024-10-25 | — | — | CN | disclosed |
| WO-2018170492-A1 | KAPPA OPIOID RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-09-20 | — | — | WO | disclosed |
| US-20180265475-A1 | HALOGENATED QUINOLINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-09-20 | — | — | US | disclosed |
| US-9828486-B2 | Halogenated polysaccharides | MANNINGTON MILLS, INC. (US) | 2017-11-28 | — | — | US | disclosed |
| WO-2017053696-A2 | HALOGENATED QUINOLINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2017-03-30 | — | — | WO | disclosed |
| US-20160280804-A1 | Halogenated Polysaccharides | MANNINGTON MILLS, INC. (US) | 2016-09-29 | — | — | US | disclosed |
| WO-2016113757-A1 | NOVEL RECYCLABLE IODINATING AGENT AND ITS APPLICATIONS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-07-21 | — | — | WO | disclosed |
| US-6225465-B1 | REACTING BENZOAZEPINE OR BENZODIAZEPINE DERIVATIVE WITH PROTECTED AMINE IN PRESENCE OF PALLADIUM CATALYST IN PRESENCE OF CARBON MONOXIDE, REMOVING PROTECTING GROUPS | SMITHKLINE BEECHAM PLC (GB) | 2001-05-01 | — | — | US | disclosed |
| EP-1019383-A2 | PROCESS FOR THE AMINOCARBONYLATION OF BENZAZEPINES AND BENZODIAZEPINES | SMITHKLINE BEECHAM PLC (GB) | 2000-07-19 | — | — | EP | disclosed |
| CN-1214045-A | Process for aminocarbonylation of benzazepines and benzodiazepines | SMITHKLINE BEECHAM PLC (GB) | 1999-04-14 | — | — | CN | disclosed |
| WO-1997024336-A2 | PROCESS FOR THE AMINOCARBONYLATION OF BENZAZEPINES AND BENZODIAZEPINES | SMITHKLINE BEECHAM PLC (GB) | 1997-07-10 | — | — | WO | disclosed |