Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.56 |
| ▸ | PPARA | Q07869 | 5/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861903 | 0.91 | GRIK1 (0.59) | GRIK1MMP2MMP3MMEFDFT1 | |
| SCHEMBL11282038 | 0.89 | PPARG (0.60) | PPARGPPARAGRIK1 | |
| SCHEMBL1860416 | 0.86 | GRIK1 (0.68) | PPARGPPARAGRIK1MMP2MMP3 | |
| SCHEMBL7924101 | 0.86 | GRIK1 (0.54) | PPARGGRIK1MMP2MMP3MME | |
| SCHEMBL3467613 | 0.85 | PPARA (0.50) | PPARGPPARAMMP2MMP3MME | |
| SCHEMBL8041638 | 0.84 | GRIK1 (0.56) | GRIK1MMP2MMP3MMEFDFT1 | |
| SCHEMBL7371830 | 0.84 | MMP2 (0.60) | PPARGPPARAGRIK1MMP2MMP3 | |
| SCHEMBL7347169 | 0.84 | MMP2 (0.60) | PPARGPPARAGRIK1MMP2MMP3 | |
| SCHEMBL7352438 | 0.84 | MMP2 (0.60) | PPARGPPARAGRIK1MMP2MMP3 | |
| SCHEMBL3466314 | 0.83 | GRIK1 (0.55) | GRIK1MMP2MMP3MMEFDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |