SCHEMBL7922590

SCHEMBL7922590

COc1cc(=O)cc2oc3ccccc3cc1-2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.50
PGR P06401 1/20 0.50
CYP1A1 P04798 1/20 0.48
CYP1B1 Q16678 1/20 0.48
AHR P35869 1/20 0.48
ERN1 O75460 1/20 0.46
MEN1 O00255 3/20 0.46
ALDH1A1 P00352 5/20 0.45
HPGD P15428 5/20 0.45
TP53 P04637 4/20 0.45
RAB9A P51151 4/20 0.45
MAPT P10636 4/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
CYP3A4 P08684 2/20 0.45
NPC1 O15118 2/20 0.45
GMNN O75496 1/20 0.45
RAF1 P04049 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26098724 0.80 KMT2A (0.50) KMT2AMEN1ALDH1A1HPGDTP53
SCHEMBL9160974 0.79 CYP1A1 (0.51) KMT2APGRCYP1A1CYP1B1AHR
SCHEMBL3985729 0.78 AHR (0.59) KMT2ACYP1A1CYP1B1AHRERN1
SCHEMBL5941127 0.78 HPGD (0.56) KMT2APGRMEN1ALDH1A1HPGD
SCHEMBL30422441 0.78 HPGD (0.56) KMT2APGRMEN1ALDH1A1HPGD
SCHEMBL9238022 0.78 RAB9A (0.49) KMT2AMEN1ALDH1A1HPGDTP53
SCHEMBL6794319 0.77 ERN1 (0.60) KMT2APGRCYP1A1CYP1B1AHR
SCHEMBL8868150 0.76 KMT2A (0.48) KMT2AMEN1ALDH1A1HPGDTP53
SCHEMBL8583022 0.76 RAB9A (0.48) KMT2AAHRMEN1ALDH1A1HPGD
SCHEMBL15390248 0.76 KMT2A (0.54) KMT2AMEN1ALDH1A1HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235485-B1 Heliothis virescens-specific and Helicoverpa zea-specific monoclonal antibodies and insect identification method MISSISSIPPI STATE UNIVERSITY 2001-05-22 US disclosed
EP-0052381-B1 PROCESS FOR PREPARING PHOTOPOLYMERIZABLE ORGANOPOLYSILOXANE COMPOSITIONS; USE OF THESE COMPOSITIONS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-08-07 EP disclosed
EP-0081444-B1 PROCESS FOR RETICULATING ORGANOPOLYSILOXANE COMPOSITIONS FREE FROM SI-H BONDS AND ETHYLENICALLY UNSATURATED ACTIVATED RADICALS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-06-19 EP disclosed
EP-0081444-A1 Process for reticulating organopolysiloxane compositions free from Si-H bonds and ethylenically unsaturated activated radicals RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-06-15 EP disclosed
EP-0016663-B1 PROCESS FOR PREPARING PHOTOPOLYMERIZABLE ORGANOPOLYSILOXANE COMPOSITIONS; USE OF THESE COMPOSITIONS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-03-23 EP disclosed
EP-0070746-A1 Liquid photopolymerisable organopolysiloxane compositions for coating purposes RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-01-26 EP disclosed
EP-0052381-A1 Process for preparing photopolymerizable organopolysiloxane compositions; use of these compositions RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1982-05-26 EP disclosed
EP-0016663-A1 Process for preparing photopolymerizable organopolysiloxane compositions; use of these compositions RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1980-10-01 EP disclosed